個(gè)人簡(jiǎn)介

基本情況

王洋，女，博士研究生，職稱：講師, 職務(wù)：無(wú)。

電子郵箱：wy15200099003@163.com

主要研究方向

疾病多組學(xué)數(shù)據(jù)融合分析及機(jī)制研究

學(xué)術(shù)兼職

山西省醫(yī)學(xué)會(huì)醫(yī)學(xué)信息學(xué)專業(yè)委員會(huì)委員

獲獎(jiǎng)情況

山西省教學(xué)成果獎(jiǎng)（高等教育研究生）一等獎(jiǎng)

代表性成果

（一）論文

1. Wang Yang; Liu Yanying; Yang Huimin; Mo Zhuang; Liu Haiyan; Yu Qi; Genetic evidence suggests a causal relationship linking thyroid function to prospective memory and dementia and Parkinson's disease, Scientific Reports, 2025

2.Wang, Yang; Li, Ying; Huang, Jie; Zhang, Yan; Ma, Ren; Zhang, Shunqi; Yin, Tao; Liu, Shangmei; Song, Yan; Liu, Zhipeng ; Correlation between electrical characteristics and biomarkers in breast cancer cells, Scientific Reports, 2021, 11(1): 0-14294

3．Wang, Y.; Hong, X.; Wang, J.; Yin, Y.; Zhang, Y.; Zhou, Y.; Piao, H-I; Liang, Z.; Zhang, L.; Li, G.; Xu, G.; Kwiatkowski, D. J.; Liu, Y. ; Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth, Oncogene, 2017, 36(6): 756-765

4. Wu L, Jiao XL, Jing M, Zhang SX, Wang Y, Li CL, Shi GX, Li ZY, Liu GL, Yan K, Yan LX, Wang Q, He PF, Yu Q. Discovery of PANoptosis-related signatures correlates with immune cell infiltration in psoriasis. PLoS One. 2024 Oct 31;19(10):e0310362. doi: 10.1371/journal.pone.0310362. PMID: 39480805; PMCID: PMC11527320.

5. Wang Q, Zhang YF, Li CL, Wang Y, Wu L, Wang XR, Huang T, Liu GL, Chen X, Yu Q, He PF. Integrating scRNA-seq and bulk RNA-seq to characterize infiltrating cells in the colorectal cancer tumor microenvironment and construct molecular risk models. Aging (Albany NY). 2023 Dec 5;15(23):13799-13821. doi: 10.18632/aging.205263. Epub 2023 Dec 5. PMID: 38054820; PMCID: PMC10756133.

6. Tang, Ling; Zeng, Jun; Geng, Pengyu; Fang, Chengnan; Wang, Yang; Sun, Mingju; Wang, Changsong; Wang, Jiao; Yin, Peiyuan; Hu, Chunxiu; Guo, Lei; Yu, Jane; Gao, Peng; Li, Enyou; Zhuang, Zhengping; Xu, Guowang; Liu, Yang ; Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma, Clinical Cancer Research, 2018, 24(2): 474-485

7. Liu, Yang; Wang, Shujun; Sun, Dongsheng; Liu, Yongdong; Liu, Yang; Wang, Yang; Liu, Chang; Wu, Hao; Lv, Yan; Ren, Ying; Guo, Xin; Sun, Guangwei; Ma, Xiaojun ; Development of a Biomimetic Chondroitin Sulfate-modified Hydrogel to Enhance the Metastasis of Tumor Cells, Scientific Reports, 2016, 6(1): 0-29858

教學(xué)、科研項(xiàng)目

1.國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目,72474125,基于多組學(xué)數(shù)據(jù)和可解釋深度學(xué)習(xí)算法的藥物預(yù)測(cè)模型的構(gòu)建及實(shí)證研究,2025-01 01 至 2028-12-31,41 萬(wàn)元,在研,參與

2.國(guó)家自然科學(xué)基金委員會(huì),面上項(xiàng)目,52077223,經(jīng)顱磁聲耦合刺 激中聲—電矢量場(chǎng)復(fù)合作用研究,2021-01-01至2024-12-31,60萬(wàn)元, 參與

3.山西省科學(xué)技術(shù)廳,山西省科技創(chuàng)新人才團(tuán)隊(duì),202304051001017, 重大疾病多源數(shù)據(jù)研究與應(yīng)用（重點(diǎn)團(tuán)隊(duì)）,2023-08至2026-08, 200 萬(wàn)元,在研,參與

4.山西省科學(xué)技術(shù)廳,山西省基礎(chǔ)研究計(jì)劃項(xiàng)目（青年項(xiàng) 目）,202203021212361,基于 PYCR1 泛癌分析探討 COPB2 通過調(diào)控脯 氨酸代謝影響腫瘤發(fā)生的作用機(jī)制,2022-05至2025-04,5萬(wàn)元,在研, 主持

5.山西省教育廳,山西省高等學(xué)？萍即蔥孿钅,2022L125,基于大 數(shù)據(jù)探討腫瘤中PYCR1介導(dǎo)的潛在分子機(jī)制研究，2022-07至2024 06,2 萬(wàn)元,在研,主持

6.c7c7.app，c7c7.app省級(jí)博士基金項(xiàng)目，SD2231,乳腺 癌電導(dǎo)率與 VEGFA 介導(dǎo)的血管生成過程的相關(guān)性分析,2022-1 至 2022-12，5 萬(wàn)，結(jié)題，主持

7.c7c7.app，c7c7.app校級(jí)博士啟動(dòng)基金項(xiàng)目，XD2141， 特發(fā)性肺纖維化潛在分子靶點(diǎn)和小分子藥物的預(yù)測(cè)和驗(yàn)證，2024-1至 2026-12，20 萬(wàn)，在研，主持

講授課程

本科生：《生物信息學(xué)》《大數(shù)據(jù)時(shí)代下的信息素養(yǎng)》《大數(shù)據(jù)基礎(chǔ)與應(yīng)用》《智能藥物設(shè)計(jì)》《腦與認(rèn)知科學(xué)概論》

碩士生：《醫(yī)學(xué)信息分析》-部分